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In this double-blind, placebo-controlled randomised clinical trial of 17,604 adults, semaglutide reduced the incidence of cardiovascular death, myocardial infarction and stroke (HR 0.80

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Probiotics also suppress MAPK signaling (e.g., p38, JNK) by limiting phosphorylation, thereby curbing amplification of inflammatory signals (Yu et al., 2024b)

The study previously demonstrated that oral semaglutide 14 mg daily reduced major adverse cardiovascular events by 14% compared to placebo over a mean follow-up of 47.5 months

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